Ultrasound Guided Cryoablation of Fibroadenomas

Hahn M, Pavlista D, Danes J, Klein R, Golatta M, Harcos A, Wallwiener D, Gruber I. Ultrasound guided cryoablation of fibroadenomas. Ultraschall Med. 2013 Feb;34(1):64-8. DOI: 10.1055/s-0032-1325460. Epub 2012 Nov 9. PMID: 23143883. 

Summary: The purpose of the study was to evaluate cryoablation of fibroadenomas under ultrasound guidance in an office-based setting using a liquid-nitrogen based system by IceCure Medical. Data was collected from 23 cryoablation procedures performed under ultrasound guidance on patients with histologically confirmed fibroadenomas with a maximum dimension of 3cm. 91.3% of the fibroadenomas treated were fully engulfed by the ice ball created during a freeze-thaw-freeze treatment cycle performed according to the size of the fibroadenoma. At 1-year follow-up, in 91% of the cases physician described the fibroadenomas as “soft” or “not palpable.” In 96% of the cases, patients and physicians rated the cosmetic results as excellent or good. The cryodestruction of fibroadenomas using a liquid nitrogen based cryoablation system proved to be functional and safe, while demonstrating meaningful reduction in volume, palpability, pain and showing satisfying cosmetic outcomes. 

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